Preclinical development of a novel plant toxin, persin, as an anti-cancer agent

Breast cancer remains a major cause of cancer death, emphasising the need for the development of new and efficient treatments. A novel plant toxin called persin shows great potential as it specifically targets the mammary gland, kills cultured breast cancer cells and makes them more responsive to the breast cancer drug, tamoxifen.

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Dr. Alison Butt
Garvan Institute of Medical Research

Breast Cancer
Exercise Trial

The introduction of an appropriate and tailored exercise and physically active program for patients following breast cancer treatment is very important. It can help to improve the well-being, physical functioning and overall quality of life to those people who have received positive outcomes to their treatment.

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Dr. Sandi Hayes
Institute of Health and Biomedical Innovation

Linking diabetes to an increased risk of breast and prostate cancer

The project will study how elevated glucose and insulin levels - the primary characteristics of Type 2 diabetes – are linked to increased risk of breast and prostate cancers. Firstly, the project will elucidate novel mechanisms of glucose- and insulin-stimulated glucose supply to and growth of breast and prostate cancer cells. Secondly, an animal models of Type 2 diabetes will be used to study how glucose and insulin promote breast and prostate tumour growth. Traditionally, diabetes and cancer have been viewed and treated as separate entities. Outcomes of the research may thus have significant implications for patient wellbeing.

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Dr Suzanne Rogers PhD
Research Fellow/
Research Group Leader
The University of Melbourne

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